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) S-Adenosylhomocysteine (SAH) Homocysteine GSH Substrate S-Adenosylmethionine (SAM) ATP Cysteine Cystathionine THE METHYLATION CYCLE CELL PLASMA 5-Methyl tetrahydrofolate monoglutamate Methionine 5-Methyl tetrahydrofolate monoglutamate (OR) 5-Methyl tetrahydrofolate polyglutamate Tetrahyrdrofolate polyglutamate Serine Glycine Formate Figure 1 Intracellular pathways of folate and homocysteine metabolism and their relation to vitamin B12 function.
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